Professor Hui graduated from the University of New South Wales in 1985. He then trained in Respiratory Medicine and Sleep Medicine in Sydney, Australia.

He was heavily involved in the clinical management of patients with SARS at the Prince of Wales Hospital during the major outbreak in 2003. He served as a WHO advisor to review the clinical management of influenza A(H5N1) during the early human outbreak in Vietnam in Feb 2004 and has since been a regular advisor to the WHO on the clinical management of severe acute respiratory infections. He joined urgent WHO missions for investigation of outbreaks of MERS in Riyadh and South Korea in 2013 and 2015 respectively. He has contributed to the WHO treatment guidelines including the clinical management of influenza A (H5N1) virus in 2007, clinical management of influenza A (H1N1) pandemic in 2009, and the Middle East Respiratory Syndrome (MERS), and the WHO training workshop in the clinical management of influenza A(H7N9) and COVID-19. He has served as an advisor to the HKSAR government on COVID-19 since Jan 2020.

Dr Hui has published over 400 peer-reviewed journal articles and 24 book chapters since joining the CUHK in 1998. He was the top 1% highly cited researcher (cross fields) in 2021 and 2022 assessed by Clarivate, with H index of 80 (Web of Science), and World’s top 2% scientists in 2021 and 2022 in addition to being ranked second and third respectively in respiratory medicine (Stanford University, Mendeley Data).